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Takashi Shichita Selected Research

Interleukin-23 (Interleukin 23)

4/2016[DAMPs (damage-associated molecular patterns) and inflammation].
7/2013[Post-ischemic innate immunity and its application for novel therapeutic strategy targeting brain inflammation].
10/2012Deleterious effect of the IL-23/IL-17A axis and γδT cells on left ventricular remodeling after myocardial infarction.
2/2012Low dose CP-690,550 (tofacitinib), a pan-JAK inhibitor, accelerates the onset of experimental autoimmune encephalomyelitis by potentiating Th17 differentiation.
1/2012Post-ischemic inflammation in the brain.
11/2010Therapeutic effect of IL-12/23 and their signaling pathway blockade on brain ischemia model.
11/2010[Role of T lymphocytes in ischemic brain injury].
8/2009Pivotal role of cerebral interleukin-17-producing gammadeltaT cells in the delayed phase of ischemic brain injury.

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Takashi Shichita Research Topics

Disease

10Inflammation (Inflammations)
01/2021 - 08/2007
7Stroke (Strokes)
10/2020 - 08/2009
6Brain Ischemia (Cerebral Ischemia)
04/2016 - 02/2005
6Infarction (Infarctions)
04/2016 - 02/2005
5Brain Injuries (Brain Injury)
06/2015 - 08/2009
4Ischemic Stroke
10/2021 - 01/2014
3Ischemia
11/2010 - 02/2005
2Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
10/2021 - 01/2021
2Pneumonia (Pneumonitis)
01/2016 - 08/2015
2Brain Infarction
08/2009 - 02/2005
1Central Nervous System Diseases (CNS Diseases)
12/2020
1Neuroinflammatory Diseases
12/2020
1Gliosis
01/2019
1Colitis
01/2017
1Neoplasms (Cancer)
01/2017
1Sepsis (Septicemia)
01/2017
1Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
01/2016
1Acute Lung Injury
01/2016
1Psoriasis (Pustulosis Palmaris et Plantaris)
09/2013
1Asthma (Bronchial Asthma)
09/2013
1Macular Degeneration (Age-Related Maculopathy)
02/2013
1Fibrosis (Cirrhosis)
10/2012
1Body Weight (Weight, Body)
02/2012
1Autoimmune Diseases (Autoimmune Disease)
02/2012
1Experimental Arthritis
02/2012
1Rheumatoid Arthritis
02/2012
1Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
02/2012
1Type 1 Diabetes Mellitus (Autoimmune Diabetes)
08/2007
1Necrosis
02/2005

Drug/Important Bio-Agent (IBA)

11CytokinesIBA
01/2021 - 02/2005
8Interleukin-23 (Interleukin 23)IBA
04/2016 - 08/2009
8Interleukin-17 (Interleukin 17)IBA
04/2016 - 08/2009
3PeroxiredoxinsIBA
04/2016 - 06/2012
2Proteins (Proteins, Gene)FDA Link
01/2021 - 06/2012
2Toll-Like Receptors (Toll-Like Receptor)IBA
11/2012 - 01/2012
2tofacitinibIBA
02/2012 - 11/2010
2Janus Kinase InhibitorsIBA
02/2012 - 11/2010
2Interleukin-6 (Interleukin 6)IBA
02/2012 - 11/2010
1phosphatidylserine receptorIBA
10/2021
1AntioxidantsIBA
01/2021
1LipidsIBA
10/2020
1Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA
10/2020
1AmphiregulinIBA
01/2019
1ErbB Receptors (EGF Receptor)IBA
01/2019
1LigandsIBA
01/2019
1MafB Transcription FactorIBA
06/2017
1tamibaroteneIBA
06/2017
1HMGB1 Protein (HMG1)IBA
01/2017
1Dextran SulfateIBA
01/2017
1Interleukin-22 (IL-22)IBA
01/2016
1EndotoxinsIBA
01/2016
1LipopolysaccharidesIBA
01/2016
1PapainIBA
08/2015
1InflammasomesIBA
06/2015
1ibrutinibIBA
06/2015
1Agammaglobulinaemia Tyrosine KinaseIBA
06/2015
1Neuroprotective AgentsIBA
01/2014
1Desmoglein 3IBA
09/2013
1AutoantigensIBA
09/2013
1Interleukin-9 (Interleukin 9)IBA
09/2013
1AntibodiesIBA
06/2012
1Therapeutic UsesIBA
11/2010
1Interleukin-12 (IL 12)IBA
11/2010
1Insulin (Novolin)FDA Link
08/2007
1Free RadicalsIBA
08/2007
1Interleukin-10 (Interleukin 10)IBA
02/2005
1beta-Galactosidase (Lactaid)IBA
02/2005
1Biotin (Vitamin H)FDA Link
02/2005
1DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA
02/2005

Therapy/Procedure

4Therapeutics
12/2020 - 11/2010
2Immunotherapy
10/2021 - 01/2017